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A multicenter clinical study on the effect of pulmonary colonization on lung cancer in patients with chronic obstructive pulmonary disease

A multicenter clinical study on the effect of pulmonary colonization on lung cancer in patients with chronic obstructive pulmonary disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077279
Enrollment
Unknown
Registered
2023-11-02
Start date
2021-04-01
Completion date
Unknown
Last updated
2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Group of lung cancer combined with COPD:None
Group of simple COPD:None
Group of lung cancer without COPD:None

Sponsors

Shanghai East Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-80 2. Gold standard diagnosis or COPD, FEV1 <80%, FEV1/FVC<70 3. Diagnosed as primary lung cancer according to Chinese Guidelines for the Diagnosis and treatment of primary lung cancer (pathologically confirmed within one month of enrollment) 4.5 Inclusion ratio of research centers: 1:1:1:1:1

Exclusion criteria

Exclusion criteria: 1.HIV positive 2. Patients with active pulmonary tuberculosis infection found through medical history or CT examination, or patients with active pulmonary tuberculosis infection history within 1 year before enrollment, or patients with active pulmonary tuberculosis infection history more than 1 year ago but without formal treatment 3. Patients with autoimmune disease assessed to interfere with the study 4. patients with other pulmonary disease assessed to interfere with the study 5. Subjects considered unsuitable for the study by the investigator for other reasons

Design outcomes

Primary

MeasureTime frame
The nucleic acid sequence;

Secondary

MeasureTime frame
TNFa;IL-1ß;IL-10;IL-17;IL-6;IFN-gamma;

Countries

China

Contacts

Public ContactLiming Zhao

Shanghai East Hospital

1976zlm@163.com+86 21 3880 4518

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026