Type 2 Diabetes
Conditions
Interventions
Comprehensive Management Group:Intestinal microbiota regulation,continuous glucose monitoring and conventional scientific management measures
General Management Group:Conventional scientific management measures
continuous glucose monitoring group:continuous glucose monitoring and conventional scientific management measures
Sponsors
The Fifth Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.patients older than 35 years old, less than 65 years of age, male and female;2.Conform to the diagnostic criteria for type 2 diabetes in the Chinese Guidelines for the Prevention and Treatment of Type 2 diabetes (2020);3.Currently using glucose-lowering medications;4.Compliance therapy, the patient and family members, voluntarily accept this study, and sign the participants informed consent.
Exclusion criteria
Exclusion criteria: 1.HbA1c=12%;2.Acute complications associated with diabetes within 3 months;3.Acute cerebrovascular accident and/or acute myocardial infarction within 6 months;4.Poor compliance and physical condition that cannot cooperate with or tolerate interventions in this study,such as mental illness,cancer,severe organ dysfunction,paralysis,severe gastrointestinal disease,et al;5.Pregnant and lactating women;6.Other situations that are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diabetes remission rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Macrogenomic analysis of intestinal microflora;Metabolomic analysis of intestinal microflora;HOMA-IR;C-peptide level;blood glucose level;HbA1c;TNF-a;IL-6;IL-10;HOMA-IS;HOMA-ß;BMI;Blood lipid level;TIR;CV; | — |
Countries
China
Contacts
Public ContactYin Kai
The Fifth Affiliated Hospital of Southern Medical University
Outcome results
None listed