Parkinson's disease
Conditions
Interventions
TI-Sham group:The first time receiveing TI stimulation, the second time receiving sham stimulation, with a 7-day interval between the two stimuli
Sham-Tl group:The first time receiveing sham stimulation, the second time receiving TI stimulation, with a 7-day interval between the two stimuli
Sponsors
School of Exercise and Health, Shanghai University of Sport
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1)idiopathic Parkinson's disease diagnosed by brain bank standard 25; 2)aged =50 years; 3)Hoehn & Yahr scale of 1.5–3; 4)Good physical condition, no personal or family history of mental illness or neurological disorders; 5)walk without assistance for at least 5 minutes in freezing of gait (FOG) or non-FOG conditions; 6)received stable medical treatment.
Exclusion criteria
Exclusion criteria: 1) any psychiatric or cognitive impairment (MoCA<24); 2)received Non-invasive brain stimulation within a week; 3) any contraindications associated with electrical stimulation (metal implants ,brain surgery, unbearable current, allergy to conductive paste or personal and family history of epilepsy; 4)have other disorders may affect gait or balance in addition to Parkinson's disease; 5)take part in another study; 6) unable to maintain good mental state during the experiment; 7) unable to understand the task; 8) vigorous physical activity within 24 hours prior to the experiment; 9) participated in other gait training within 1 month before the experiment; 10) diagnosed cardiovascular risk factors associated with exercise .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA) ;Blind effects and adverse questionnaire;UNIFIED PARKINSON'S DISEASE RATING SCALE-?, MDS-UPDRS-?;Lee version Visual Analogue Scale to Evaluate Fatigue Severity, VAS-F;Balance biomechanical index ;Gait biomechanical index ; | — |
Secondary
| Measure | Time frame |
|---|---|
| New Freezing Of Gait Questionnaire;Electromyography index;Dual-task cost;Complete time of Time Up and Go test; | — |
Countries
China
Contacts
Public ContactYu Liu
Shanghai University of Sport
Outcome results
None listed