cytomegalovirus retinitis after bone marrow transplantation
Conditions
Interventions
Case series:none
Sponsors
The Second Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Patients who received allogeneic hematopoietic stem cell transplantation (allo-HSCT) due to any potential malignant hematological disease or non-malignant diseases, and were at least 18 years old at the time of allo-HSCT. ? Patients who were clinically diagnosed with Cytomegalovirus Retinitis (CMVR) based on clinical symptoms and ophthalmological examination. ? Patients who had aqueous humor samples sent for CMV nucleic acid testing and inflammatory factor detection. ? Patients who received ophthalmological or internal antiviral treatment for CMVR after allo-HSCT, and had a treatment plan and follow-up records. ? Patients who had complete medical records, including pre-transplant evaluation, transplant details, and post-transplant follow-up data.
Exclusion criteria
Exclusion criteria: ? Patients who had a history of CMVR prior to receiving allo-HSCT. ? Patients with concurrent eye infections or inflammations that might interfere with the accurate diagnosis and treatment of CMVR. ? Patients who received non-allogeneic stem cell transplantation (such as autologous or syngeneic transplant). ? Patients who did not receive any antiviral treatment for CMVR after allo-HSCT. ? Patients whose medical records were incomplete or missing, impacting the accurate evaluation of research objectives
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunosuppressive therapy used;Viral serological tests and viral load levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Donor type;Presence of GVHD; | — |
Countries
China
Contacts
Public ContactLiu Fei
The Second Hospital of Dalian Medical University
Outcome results
None listed