postoperative delirium
Conditions
Interventions
case series:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University, Chongqing
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: ASA Class II to III, over 65 years old, first non-cardiac surgery patients, 18kg/m2= body mass index =28kg/m2, gender is not limited, operation time =4h, signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Preoperative complication of Kashin-beck disease; 2.Inability to communicate before surgery (e.g.coma, deep dementia, speech impairment or severe visual or hearing impairment); 3.Preoperative brief mental state examination (MMSE) score (illiterate < 17 points, primary level < 20 points, secondary level [including technical secondary school] and above < 24 points); 4.Having serious heart, liver, kidney and metabolic diseases; A history of neurological or mental illness; Taking psychotropic drugs; Patients who had previously undergone intracranial surgery (which could affect neurophysiological signals); 5.Emergency surgery, acute infection, and did not have informed consent or participate in other clinical trials were admitted to the ICU after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium;Sleep score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of postoperative delirium;Blood selenium level before and after anesthesia;Glutathione peroxidase levels before and after surgical anesthesia;Serum inflammatory factors before and after surgical anesthesia; | — |
Countries
China
Contacts
Public ContactLi Ping
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed