Frailty
Conditions
Interventions
Frailty group:The dose of sufentanil was 0.10 µg/kg in the first patient. If a positive response occurred at the time of rigid scope placement, the dose of sufentanil in the next patient was elevated
Control group:The dose of sufentanil was 0.10 µg/kg in the first patient. If a positive response occurred at the time of rigid scope placement, the dose of sufentanil in the next patient was elevated
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Elderly patients aged =65 years for elective rigid bronchoscopic interventions (2) Body mass index (BMI) 18-30 kg/m2 (3) Consent to participate in this study
Exclusion criteria
Exclusion criteria: (1) Those who are already using vasopressors drugs (e.g., norepinephrine, etc.) to maintain blood pressure before surgery; (2) Those with a history of angina pectoris, myocardial infarction, or heart failure in the past 3 months; (3) History of transient ischemic attack, stroke in the past 3 months; (4) Those who are unable to complete the preoperative evaluation due to end-stage diseases; (5) Long-term use of analgesics; (6) Emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality on the night after surgery;Pain score on postoperative day 1;Incidence of delirium 4 days after surgery;Length of postoperative hospitalization;Incidence of major complications within 30 days after surgery; | — |
Countries
People's Republic of China
Contacts
Public ContactDongxin Wang
Peking University First Hospital
Outcome results
None listed