mild cognition impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) meet the diagnostic criteria for mild cognitive impairment; (2) Be between 50~80 years old and have no gender limit; (3) Neuropsychological testing satisfies 19=MoCA-B=24; (4) Be able to communicate proficiently in Chinese and cooperate with the completion of cognitive function examination; (5) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Other medical or neurological diseases that may be associated with cognitive impairment, such as cerebrovascular disease, encephalitis, metabolic encephalopathy, multiple sclerosis, normal intracranial pressure hydrocephalus, brain tumors, traumatic brain injury, epilepsy, Parkinson's disease, etc.; (2) Other systemic diseases that can cause cognitive impairment (such as liver insufficiency, renal insufficiency, severe anemia, alcohol consumption and drug abuse, etc.); (3) vascular dementia or other neurodegenerative diseases not diagnosed by the AD spectrum; (4) Those with mental illnesses such as moderate to severe depression (Hamilton Depression Scale score = 14) (5) Those who are severely aphasia or physically disabled or deprived of use and cannot complete neuropsychological examination. (6) Have an acute or severe life-threatening illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive assessment, MOCA-B; | — |
Secondary
| Measure | Time frame |
|---|---|
| AVLT-H;STT-A&B;AFT;BNT;MRI;EEG;HRV;PSQI;HAMD-17;HAMA-14; | — |
Countries
China
Contacts
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences