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A double blind randomized clinical trial of transcutaneous electrical stimulation of auricular acupuncture points in patients with mild cognition impairment

National Key Research and Development Program: Brain Characterization and Organ Regulation of External Ear-Zongyi Function (2022YFC3500501) A double blind randomized clinical trial of transcutaneous electrical stimulation of auricular acupuncture points in patients with mild cognition impairment

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077209
Enrollment
Unknown
Registered
2023-11-01
Start date
2023-11-01
Completion date
Unknown
Last updated
2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognition impairment

Interventions

Sponsors

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) meet the diagnostic criteria for mild cognitive impairment; (2) Be between 50~80 years old and have no gender limit; (3) Neuropsychological testing satisfies 19=MoCA-B=24; (4) Be able to communicate proficiently in Chinese and cooperate with the completion of cognitive function examination; (5) Sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Other medical or neurological diseases that may be associated with cognitive impairment, such as cerebrovascular disease, encephalitis, metabolic encephalopathy, multiple sclerosis, normal intracranial pressure hydrocephalus, brain tumors, traumatic brain injury, epilepsy, Parkinson's disease, etc.; (2) Other systemic diseases that can cause cognitive impairment (such as liver insufficiency, renal insufficiency, severe anemia, alcohol consumption and drug abuse, etc.); (3) vascular dementia or other neurodegenerative diseases not diagnosed by the AD spectrum; (4) Those with mental illnesses such as moderate to severe depression (Hamilton Depression Scale score = 14) (5) Those who are severely aphasia or physically disabled or deprived of use and cannot complete neuropsychological examination. (6) Have an acute or severe life-threatening illness.

Design outcomes

Primary

MeasureTime frame
Montreal cognitive assessment, MOCA-B;

Secondary

MeasureTime frame
AVLT-H;STT-A&B;AFT;BNT;MRI;EEG;HRV;PSQI;HAMD-17;HAMA-14;

Countries

China

Contacts

Public ContactRong Peijing

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences

drrongpj@163.com+86 137 1848 2149

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026