Breast cancer
Conditions
Interventions
Sponsors
Yantai Yuhuangding Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.the patients were confirmed by biopsy as invasive breast cancer with ipsilateral ALN metastases; 2.the patients should have adequate hematologic, liver, and renal function at enrollment; 3. the enrolled patients were planned to receive a standard NAC treatment, followed by ALND; patients who have been undergoing or have completed the standard NAC waiting for the surgery will also deemed eligible; 4.axillary lymph node pathological NAC response (pCR or non-pCR) was confirmed; 5.MRI and whole slide imaging (WSI) of biopsy were available; both MRI and biopsy were conducted within 2 weeks before NAC; 6.no other tumor occurred during NAC and operation.
Exclusion criteria
Exclusion criteria: 1.a history of chemoradiation therapy, surgery, or malignancy; 2.the patients received non-standard treatment or did not complete the NAC regimen; 3.no surgery was performed or the results of postoperative pathology were incomplete; 4.lack of clinical information, MRI images, and WSI for analysis requirements; 5.insufficient quality of MRI images or WSI; 6.patients with multifocal, bilateral, or occult breast cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under receiver operating characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy; | — |
Countries
China
Contacts
Public ContactNing Mao
Yantai Yuhuangding Hospital
Outcome results
None listed