sarcopenia
Conditions
Interventions
Intervention group:Dietary exercise guidance+nutritional supplementation+exercise intervention
Control group:Dietary exercise guidance
Sponsors
Huadong hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with sarcopenia (according to the Asian Sarcopenia Working Group AWGS 2019 diagnostic criteria) ? Skeletal muscle mass index of limbs: male <7.0kg/m2, female <5.7kg/m2 (bioelectrical impedance BIA assay was used in this study); ? Grip strength: male <28kg, female <18kg and/or 5 sitting times ?12s/6m Walking speed <1.0m/s (2) Age: =65 years old, gender is not limited (3) Self-care, no need for special care, no bad habits such as alcoholism (4) have lived locally for nearly 3 months and are not expected to leave their residence within 6 months (5) Voluntarily participate in this experiment and sign the informed consent
Exclusion criteria
Exclusion criteria: (1) Patients with severe stroke, cognitive dysfunction and mobility impairment (2) Previous history of mental illness, or understanding, hearing, visual impairment, unable to communicate normally (3) People with severe gastrointestinal diseases (severe chronic diarrhea, nausea, vomiting, gastrointestinal obstruction, inflammatory bowel disease, etc.) or severe malnutrition (4) There are sports contraindications: such as serious musculoskeletal disorders or heart, liver, kidney and other important organ insufficiency; History of spinal nerve injury (5) Implantation of electronic devices or metals in the body (6) People who may be allergic to the intervention diet (7) Those who are taking various protein supplements (equivalent to an additional daily supplement of protein ?10g) or participating in other clinical trials (8) There are other signs of significant medical or mental illness that the respondent considers unsuitable for participating in the study(YNMT)·
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle index(SMI);Grip;SPPB;MNA-SF;FRAIL;25(OH)D3;Calf circumference; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24h Dietary survey;EQ-5D;BMI;Liver function;Renal function; | — |
Countries
CHINA
Contacts
Public ContactJianqin Sun
Huadong hospital affiliated to Fudan University
Outcome results
None listed