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The clinical profile, genetic basis and survival of childhood cardiomyopathy: a retrospective study in single-center

The clinical profile, genetic basis and survival of childhood cardiomyopathy: a retrospective study in single-center

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077160
Enrollment
Unknown
Registered
2023-11-01
Start date
2023-11-01
Completion date
Unknown
Last updated
2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiomyopathy

Interventions

Restrictive cardiomyopathy:None
Left Ventrichlar Non-Compaction Cardiomyopathy:None

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Among patients with CM, eligible subjects were confined to those who exhibited intrinsic abnormalities of the myocardium. The inclusion criteria for DCM were left ventricular dilation (left ventricular end diastolic diameter = 2 SD above normal for body-surface area), simultaneously reduced left ventricular systolic function (left ventricular ejection fraction (LVEF) = 2 SD below normal for age), and an absence of secondary causes of ventricular dilation. Diagnosis of HCM was based on left ventricular hypertrophy (a wall thickness = 2 SD above the normal population mean for body surface area), excluding defined hemodynamic causes such as congenital heart disease, hypertension, or exposure to drugs known to result in cardiac hypertrophy. Meanwhile, RCM patients included children who exhibited enlarged atria without ventricular dilatation in the absence of congenital, valvular, or pericardial disease. Finally, patients were diagnosed with LVNC as de?ned by the Jenni criteria.

Exclusion criteria

Exclusion criteria: Children with ventricular dilatation caused by secondary factors. Hypertrophic cardiomyopathy caused by congenital heart disease, hypertension, or exposure to drugs known to cause hypertrophy of the heart. Family members refuse to participate or do not cooperate.

Design outcomes

Primary

MeasureTime frame
survival time;NYHA/Ross class;Gene test;

Secondary

MeasureTime frame
Result of ECG;Result of echocardiography;

Countries

China

Contacts

Public ContactJunjun Quan

Children's Hospital of Chongqing Medical University

junjunquan1002@163.com+86 187 0232 4525

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026