Anxiety, infertility
Conditions
Interventions
Control group:NO
Case group:Intestinal probiotic intervention
Sponsors
Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) There were 60 patients who had not been pregnant for more than 1 year and met the clinical diagnosis criteria of infertility, all of whom were newly diagnosed patients in the reproductive Department of Nanchang Reproductive Hospital; (2) Age 20-40 years old, BMI =28kg/m2; . (3) All participants were aware of the content of this study and voluntarily signed informed consent without contraindications. (4) no chronic diseases such as hypertension and diabetes, no malignant diseases such as cancer; (5) no digestive diseases such as constipation and diarrhea, and no serious diseases of other systems; (6) No oral antibiotics or probiotics in the past month; (7) All the enrolled people have the education level of junior high school or above, and can understand and complete the relevant self-assessment scale by themselves.
Exclusion criteria
Exclusion criteria: (1) Failure to complete the research or incomplete questionnaire information; (2) Use of psychotropic drugs, steroid hormones or drugs that affect hormone secretion in the past 3 months; (3) traumatic life events, family history of mental illness, organic brain and serious physical illness; (4) Patients with heart or kidney diseases, digestive diseases, hypertension, cancer, diabetes, constipation, diarrhea; (5) Patients with definite decline in ovarian function, such as premature ovarian insufficiency and premature ovarian failure, caused by surgery; (6) hypothalamic or pituitary amenorrhea; (7) Patients who have taken antibiotics or probiotics orally within the last 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The differences of intestinal flora structure and sex hormone levels between anxious and non-anxious people were analyzed; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal flora affects anxiety, depression-like behavior and pregnancy outcome in mice; | — |
Countries
China
Contacts
Public Contactchenweijun
Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine
Outcome results
None listed