Chronic pain in elderly patients with comorbid type 2 diabetes mellitus
Conditions
Interventions
Experimental group:The experimental group was treated with minimally invasive glucocorticoids (3.5 mg/m2= GCs < 7 mg/m2).
Control group:The control group was treated with minimally invasive glucocorticoids (GCs< 3.5 mg/m2).
Sponsors
Department of Pain Management,West China Hospital,Sichuan University
Eligibility
Sex/Gender
All
Age
65 Years to 99 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with type 2 diabetes mellitus comorbid chronic pain in the elderly (mainly including lumbar intervertebral disc herniation disease, cervical spondylosis, herpes zoster-related neuralgia). (2) Male or female, age > 65 years old, weight 45~75kg, disease course more than 3 months. (3) The coagulation function is normal, and there are no contraindications to puncture. (4) Good blood sugar control and no diabetes-related complications. (5) No history of hormone use within 3 months. (6) Have not participated in other clinical studies within 3 months.
Exclusion criteria
Exclusion criteria: (1) Type I diabetes. (2) Patients with glucocorticoid allergy. (3) Lesions at the puncture site: vertebral tumors, lumbar tuberculosis, spinal canal infection, huge protrusions in patients with lumbar intervertebral disc herniation, cauda equina syndrome, etc. (4) Severe cardiopulmonary insufficiency. (5) Patients with inflammation, infection and skin diseases at the puncture site. (6) Patients with organ dysfunction due to diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue score ,VAS;Fasting blood glucose and blood glucose 2 hours postprandial time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects;Hospital stay;Hospital costs;Follow-up medication costs; | — |
Countries
China
Contacts
Public ContactLing Ye
Department of Pain Management,West China Hospital,Sichuan University
Outcome results
None listed