mycoplasma pneumoniae pneumonia
Conditions
Interventions
Group of mycoplasma pneumoniae pneumonia:None
Sponsors
Wuhan Science and Technology Bureau
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 1-18 years who are clinically diagnosed with MPP have clinical manifestations of pneumonia such as cough and fever and/or imaging changes, and are positive for MP etiology (positive for MP nucleic acid; The single MP antibody titer was = 1:160, and the MP antibody titer was increased or decreased by 4 times or more in the convalescent and acute stages). 2. Patients have large lung consolidation, with or without pleural effusion and atelectasis in Chest CT, and require the treatment with bronchoscopic alveolar lavage.
Exclusion criteria
Exclusion criteria: 1. Children who are not suitable, or do not agree to bronchoalveolar lavage. 2.Children who suffered from a serious disease, such as cardiovascular disease, kidney disease, liver disease, blood disease, serious infection or tumor. 3. Children who received azithromycin treatment within 4 weeks before receiving the azithromycin protocol applied in this study. 4. Children who are allergic to azithromycin. 5. Children who participate in other clinical studies within 4 weeks prior to admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| azithromycin concentration in blood;azithromycin concentration in BALF; | — |
Secondary
| Measure | Time frame |
|---|---|
| azithromycin concentration in cell suspension; | — |
Countries
China
Contacts
Public ContactLu Xiaoxia
Wuhan Children's Hospital
Outcome results
None listed