Multiple sclerosis
Conditions
Interventions
Experimental group (multiple sclerosis patients):None
Control group (10 patients with other central nervous system demyelinating diseases, 10 patients with myasthenia gravis, and 30 healthy volunteers):None
Sponsors
The Second Xiangya Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Meet the 2017 McDonald adult MS diagnostic criteria; 2) Patients diagnosed with demyelinating diseases of the central system according to clinical symptoms and examinations; 3) Patients diagnosed with myasthenia gravis based on clinical symptoms and examination; 4) No immunosuppressants or interferon drugs were taken for 3 months before treatment; 5)EBV infection was positive.
Exclusion criteria
Exclusion criteria: 1) Other autoimmune diseases, such as systemic lupus erythematosus, ankylosing spondylitis, autoimmune hepatitis, Sjogren's syndrome, etc.; 2) Tumor patients; 3) Previous history of cerebral infarction, cerebral hemorrhage, and cerebral trauma; 4) combined with systemic active infection; 5) Depression, mania, schizophrenia and other mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| B cell percentage;Cholesterol metabolite; | — |
Countries
China
Contacts
Public ContactHu Zhaolan
The Second Xiangya Hospital, Central South University, 139 Renmin Middle Road, Furong District, Changsha City, Hunan Province
Outcome results
None listed