Subject cognitive decline,SCD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Comply with SCD and MPS diagnostic standards; ? Having the ability to complete cognitive ability tests and other tests specified in the plan; ? Women over the age of 40 and residing locally for a long time; ? Completing informed consent.
Exclusion criteria
Exclusion criteria: ? Excluding SCD caused by other reasons; ? Excluding organic lesions such as brain injury; ? Those under the age of 40; ? There are abnormal laboratory indicators; ? There are other situations where it is impossible to complete this study; ? There are unstable or severe organic lesions such as the heart.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive ability level;Assessment of menopausal syndrome;Estrogen and androgen levels;Aß42/Aß40 & p-Tau in plasma; p-Tau in plasma; | — |
Secondary
| Measure | Time frame |
|---|---|
| Homocysteine;Blood routine;biochemistry; | — |
Countries
China
Contacts
Luohe Central hospital