Effect of colostrum oral immunotherapy with different doses on outcomes of very low birth weight infants

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300077114

Enrollment

Unknown

Registered

2023-10-31

Start date

2023-11-01

Completion date

Unknown

Last updated

2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive diseases

Interventions

control:Routine care

Trial 1:Colostrum orally applied every 3 hours

Trial 2:Colostrum orally applied every 6 hours

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Maternal age =18 years, consent to breastfeeding.? Preterm birth weight < 1500g.? After delivery, the children were transferred directly to the neonatology department NICU.

Exclusion criteria

Exclusion criteria: ? The child or mother has a contraindication to breastfeeding, or cannot breastfeed for other reasons.? Chromosomal disease or congenital abnormality.? Unwilling to participate in this researcher.

Design outcomes

Primary

Measure	Time frame
Necrotizing enterocolitis;Bronchopulmonary dysplasia;Retinopathy prematurity;The time to full enteral feeding;	—

Secondary

Measure	Time frame
Feeding intolerance;duration of mechanical ventilation;length of stay;hospitalization cost;Interleukin-2;Interleukin-4;Interleukin-6;Interleukin-10;sIgA;	—

Countries

China

Contacts

Public ContactZhen Yan FU

Affiliated Hospital of Zunyi Medical University

2568448305@qq.com+86 28609055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026