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Canceled by the investigator. Randomized Controlled Trials of Danggui Sini Decoction in Treatment of Arteriosclerosis Obliterans of Cold Blood Coagulation and Blood Stasis Type

Randomized Controlled Trials of Danggui Sini Decoction in Treatment of Arteriosclerosis Obliterans of Cold Blood Coagulation and Blood Stasis Type

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077107
Enrollment
Unknown
Registered
2023-10-31
Start date
2023-11-01
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arteriolesclerosis obliterans

Interventions

Control group:Cilostazol tablets
Integrated group:Danggui Sini Decoction integrated with cilostazol tablets

Sponsors

Xingcheng Hospital of Tradioanl Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? Meet the diagnostic standards of traditional Chinese medicine and Western medicine mentioned above; ? Age>40 years old; ? Living independently, moving freely, with normal mental and cognitive functions; ? Complete clinical data; ? Voluntarily participate in this study and sign an informed consent form; ? 0.5<ABI = 0.90.

Exclusion criteria

Exclusion criteria: ? Hemorrhagic patients (such as hemophilia, capillary fragility, intracranial hemorrhage, gastrointestinal bleeding, urinary tract bleeding, hemoptysis, vitreous hemorrhage, etc.); ? Patients with poor compliance, failure to receive treatment as required, or self medicating with other treatment measures; ? Patients with organic liver, kidney, and lung lesions such as liver injury, renal insufficiency, and respiratory failure; ? Patients with severe cardiovascular and cerebrovascular diseases, as well as patients with congestive heart failure, who are accompanied by or have experienced acute coronary syndrome, cerebral hemorrhage, cerebral thrombosis, etc.; ? Pregnant or lactating women, and patients in preparation for pregnancy and childbirth; ? Patients with autoimmune, infectious diseases and lower limb ulcers; ? Urgent surgical reconstruction of arterial access; ?Patients with a history of allergies to the drugs used in the experiment.

Design outcomes

Primary

MeasureTime frame
ABI;Toe temprerature ;Neutrophil/lymphocyte ratio, NLR;

Secondary

MeasureTime frame
Blood pressure, blood sugar, blood lipids, blood routine, urine routine, liver function, kidney function, electrocardiogram;

Countries

China

Contacts

Public ContactZheng Chengjun

Xingcheng Hospital of Traditional Chinese Medicine

2930085362@qq.com+86 139 4298 8306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026