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Design of melanin-sanshool functional material and its protective effect on skin photodamage/photoaging

Design of melanin-pyrroxanthin functional material and its protective effect on skin photodamage/photoaging

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077100
Enrollment
Unknown
Registered
2023-10-31
Start date
2023-10-31
Completion date
Unknown
Last updated
2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin photodamage/photoaging

Interventions

melanin?sanshool functional material:Apply 0.2g of melanin?sanshool functional material daily
Vitamin E lotion:Apply 0.2 grams of vitamin E lotion daily

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Patients clinically diagnosed with skin photoinjury; 2) Age 18 to 60 years old; 3) The patient voluntarily participated in this clinical study and signed a written informed consent form.

Exclusion criteria

Exclusion criteria: 1) Exposure to other skin diseases such as melasma, freckles, and seborrheic dermatitis at the exposed site may affect the judgment of the test results; 2) Individuals with allergies to experimental drugs or high sensitivity constitution; 3) Pregnant, quasi pregnant, or lactating patients; 4) The laboratory examination results of liver function and kidney function were judged by the doctor as clinically significant abnormalities; 5) Patients who took oral antioxidant drugs or topical hormone drugs within 4 weeks before the trial; Patients who have undergone physical therapy for skin photodamage; 6) Patients with a history of facial injection or surgery 2 months prior to the trial; 7) Patients with immunodeficiency diseases.

Design outcomes

Primary

MeasureTime frame
Total effective rate;safety;

Secondary

MeasureTime frame
Skin loss reduction rate;Skin lesion score;VISIA score improvement rate;Skin detector checks skin barrier function;

Countries

China

Contacts

Public ContactXian Jiang

Department of Dermatology, West China Hospital, Sichuan University.

531187781@qq.com+86 189 8060 1693

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026