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Mitochondrial endoplasmic reticulum coupling and susceptibility to ischemic cardiomyopathy and the mechanism of myocardial remodeling

Mitochondrial endoplasmic reticulum coupling and susceptibility to ischemic cardiomyopathy and the mechanism of myocardial remodeling

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077091
Enrollment
Unknown
Registered
2023-10-30
Start date
2021-09-05
Completion date
Unknown
Last updated
2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic cardiomyopathy

Interventions

Sponsors

Ailiman Mahemuti
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: (1) inclusion criteria: 1.diagnosed as coronary artery disease by CAG , one or more main coronary artery exists a stenosis bigger than 50%, or have a history of ACI and have the history of PCI or CABG. (2) Myocardial function is impaired, manifested as N-terminal pre-B-type natriuretic peptide (NT-proBNP) >125ng\/mL. (3) Predictable angina pectoris, which can be relieved by taking Grest or nitroglycerin. (4) Symptoms of chest tightness, shortness of breath, and dyspnea can usually be quickly relieved by rest.

Exclusion criteria

Exclusion criteria: 1.acute decopansated heart failure 2.hemodynamic instability 3.have a history of liver disease, renal disease,hemopathy, autoimmune disease 4. expected survival perido <1 year non heart disease 5.cachexia

Design outcomes

Primary

MeasureTime frame
have a disease or not;

Countries

China

Contacts

Public ContactAiliman Mahemuti

first affiliated hospital of xinjiang medical university

ailiman623@163.com+86 136 3997 0300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026