Post-stroke dysarthria
Conditions
Interventions
control group:Pronunciation task using conventional sound (80dB) as start-up signal
Experimental group:A startle-stimulated sound (114 dB) was used as a start signal for the articulatory task
Sponsors
Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for healthy subjects: ? Age 18-80 years old, male or female. ? Chinese as mother tongue, can communicate in Mandarin, elementary school diploma or above ? Good tolerance to sudden sound stimulation of 114 dB. ? Signed an informed consent form, volunteered to participate in this trial, and were able to complete the trial Inclusion criteria for patients with post-stroke dysarthria: ? Age 18-80 years old, male and female; ? Meet the diagnostic criteria of stroke (confirmed by clinical CT or MRI for the first occurrence of stroke) Patients are conscious, vital signs are stable, and the duration of stroke is 2 weeks to 6 months. Patients with mild-moderate dysarthria as assessed by the Comprehensive Assessment Scale for Dysarthria (Frenchay Assessment Method). (iv) Native speakers of Chinese, who could communicate in Mandarin in daily life before the onset of stroke, and who had an elementary school diploma or above. ?No history of hearing damage and good tolerance to sudden sound stimulation at 114 dB. ? Sign the informed consent form, participate in the trial voluntarily, and be able to complete the trial.
Exclusion criteria
Exclusion criteria: ? Subjects with a history including pregnancy, dizziness, poor mental status, seizures, psychiatric illness, and/or a combination of serious cardiovascular, hepatic, or renal serious illness within the last year. (ii) History of other diseases affecting swallowing, speech, and/or language, such as dementia, Parkinson's disease, or oral cancer [13]; (iii) Patients with BDAE aphasia severity assessment grade 3 or less (iv) Patients with severe cognitive impairment as assessed by MMSE (MMSE score < 20) [41]. ? Excluding patients with vocal cord paralysis, hearing impairment, and visual impairment. (vi) Excluding patients with damage or lesions to the organs or muscles involved in sound formation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acoustic Indicators;Positive rate of startle reaction;Oxyhemoglobin and deoxyhemoglobin concentrations in cerebral cortical regions of interest; | — |
Countries
China
Contacts
Public ContactLu Min
Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed