knee injuries
Conditions
Interventions
S group:Sodium sugamose was given intravenously 2mg/kg
Control group:Intravenous injection of Neostigmine 0.05mg /kg combined with atropine 0.01mg/kg
Sponsors
The affiliChangzhou No.2 People's HospitalNanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) induction and maintenance of total knee replacement with rocuronium as a muscle relaxant 2) Age =18 years 3) ASA classification ?-? 4) Informed consent, voluntary participation in the trial, signed by the patient
Exclusion criteria
Exclusion criteria: 1) Patients treated with toreimifene or fusidic acid before or immediately after surgery 2) Patients with limitations in BIS monitoring, such as a history of central brain injury, psychotropic drug treatment, presence of pacemaker or Parkinson's disease 3) severe renal insufficiency (creatinine clearance <30ml/min) 4) patients with hypersensitivity and hypersensitivity to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| extubation time;bispectral index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Residual muscle relaxation;postoperative pulmonary complications;Early postoperative ambulation time;hospital stay;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactYun Huifang
Changzhou No.2 People's Hospital
Outcome results
None listed