None
Conditions
Interventions
Case series:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Unlimited race and nationality, between aged 18 and 40, can be proficient in Chinese or English reading and writing ability, there is no blood donation reaction in the past; 2.Weight: Male =50kg, female =45kg and 18.5kg/? = BMI = 30kg/? (BMI, weight index = weight (kg) ÷ height (m) 2); 3. Blood pressure: 12.0kPa (90mmHg) = systolic blood pressure <18.7kPa (140mmHg), 8.0kPa (60mmHg) = diastolic pressure <12.0kPa (90mmHg); 4. Pulse: 60 times/min ~ 100 times/min, highly endurance athletes =50 times/min, neat rhythm; 5. Body temperature: 36.3-37.2 ?; 6. The general situation of the whole body is good: the damage of important organs such as no heart, lungs, liver, and kidneys, no serious or uncontrolled infection, no serious history of mental disorders; 7. Clinical examination must meet the following standards: hemoglobin (HB) measurement: Male =120g/L, female =110g/L. For example, copper sulfate method: male =1.0520, female =1.0510; white blood cells (WBC) measurement: 4-10x109/L; Alanine aminotransome (ALT) = 40U/L (rate method), =25U/L (Lai (Lai (Lai (Lai) Method); hepatitis A virus antibody (HAV antibody) negative; hepatitis B virus surface antigen (HBSAG) negative; hepatitis C virus antibody (HCV antibody) negative; human immune deficiency virus antibody (HIV-1 and HIV-2 Antibody) negative; syphilis negative; EPSTEIN-BARR virus antibody (EBV antibody) negative.
Exclusion criteria
Exclusion criteria: 1. The age of more than 18-40 years of age; 2. There are respiratory, circulation, digestion, urology, blood, immunity, endocrine system diseases or metabolic disorders; those who have neurological diseases, mental illness, Ke-Ya disease, and family medical history may be derived from Keya-Ya Pathogenic infection tissue or tissue derivatives; 3. Those who have infectious diseases including hepatitis A, hepatitis B, hepatitis C, HIV, and syphilis; 4. There are chronic skin diseases, especially infectious, allergic or inflammatory whole body skin diseases; those with allergic diseases or recurrent allergies; 5. Those who have malignant tumors or benign tumors affecting health; 6. Examination shows that blood pressure, heart rate, hemoglobin, liver and kidney function, ECG detection, etc. are abnormal and clinically significant; 7.Those with less than 3 months of surgery, such as appendix resection, and after ophthalmology surgery, etc.; Major surgery for less than 1 year, such as: gynecological benign tumor, body surface benign tumor surgery, etc.; 8. Women's pregnancy and abortion have less than 6 months after abortion, and those who have giving birth and lactation less than 1 year; 9. The more than 1 week of disease, the more than one week of the respiratory tract infection, or the more than 3 months of pneumonia; 10. The more than 3 months of acute pyelone nephritis, or the urinary system of the stones of the urinary system; 11. Injury or pollution wounds contaminated by blood or tissue liquid, or those who have been performed for less than 1 year after tattooing; 12.Those who have accepted the infusion of the whole blood and blood component within 1 year; 13.Accepting measles, mumps, or spinal ash, and other poisoning live vaccines such as the last vaccination of the last vaccination of the last vaccine, or the rubella vaccine, the human rabies vaccine, and the encephalitis poisoning vaccine, etc. Inner; 14. Those who are injected with rabies vaccine after being bitten by animals in the last 1 year of immunization; 15. Accept the last 4 weeks of the last vaccination of antitoxin or immunotherapy injection, or accept the last vaccination of the hepatitis B immunoglobulin injection; 16.There will be clinical trial records within 3 months; 17.Researchers believe that the subject is not suitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peripheral blood mononuclear cell collection quantity; | — |
Countries
China
Contacts
Public ContactHu Haiyan
Shanghai Sixth People's Hospital
Outcome results
None listed