patients undergoing bariatric surgery
Conditions
Interventions
Group E:Received general anesthesia and regional nerve block anesthesia, while group E was induced and maintained using Remimazolam. Maintain total intravenous anesthesia with Remimazolam 1-3mg/kg/h
Group C:Received general anesthesia and regional nerve block anesthesia, and group C was induced and maintained with propofol. Maintain total intravenous anesthesia with propofol 4-12mg/kg/h and remif
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1.1) diagnosed with obesity(BMI=30) , plan to undergo laparoscopic sleeve gastrectomy; (1.2)18=Age=60,Gender unlimited; (1.3)ASA ?~?; (1.4)Clearly understand, voluntarily participate in the study, and have their informed consent form signed by themselves
Exclusion criteria
Exclusion criteria: (2.1) Concomitant severe cardiovascular, pulmonary, and cerebral diseases, such as uncontrolled hypertension, coronary heart disease, congenital heart disease, valve disease, intracranial vascular malformations, asthma , COPD , etc; (2.2) Have a history of drug abuse; (2.3) Communication disorders, inability to cooperate with researchers, such as language comprehension disorders, mental illness, etc.; (2.4) A history of allergy to benzodiazepines; (2.5) Contraindications to pulmonary recruitment maneuvers (such as bullous lung disease), hemodynamic instability; (2.6) Patients who have used drugs that have a significant effect on the central nervous system in the past 3 months, or who have hearing loss or epilepsy. (2.7) Pregnant women; (2.8) Participants in other clinical trials within 3 months prior to study enrollment; (2.9) Other conditions deemed unsuitable for inclusion by the researcher.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting;Postoperative Pain;Postoperative recovery of gastrointestinal function;Postoperative recovery time;Recovery time required for tracheal extubation;Postoperative oxygenation index; | — |
Primary
| Measure | Time frame |
|---|---|
| depth of anesthesia;Time weighted average of hypotension; | — |
Countries
China
Contacts
Public ContactWei Ke
Anesthesiology Department of the First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed