nonalcoholic fatty liver disease,NAFLD
Conditions
Interventions
patients with non-obese fatty liver disease:NA
patients with obese fatty liver disease:NA
Sponsors
Beijing Youan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) pathological liver adipose area =5% (2) aged between 18 and 80 years (3) agree to sign the informed consent
Exclusion criteria
Exclusion criteria: (1) Lack of necessary demographic indicators, body measurement indicators, laboratory indicators, etc (2) Lack of necessary prior history and medication history (3) Liver disease with other causes, such as HBV, HCV infection, autoimmune liver disease and other diseases; A history of heavy alcohol consumption (alcohol intake > 210g/ day for men and > 140g/ day for women); Secondary hepatic steatosis caused by drugs, such as tamoxifen, hormones, etc (4) Combined with other serious diseases that may affect the nutritional status of the body, such as malignant tumors, serious organic diseases of the heart, lungs, kidneys, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MBOAT7 rs641738 gene polymorphism;liver adipose area; | — |
Secondary
| Measure | Time frame |
|---|---|
| pathological score and non-invasive liver fibrosis score;liver function, blood routine, blood lipid, blood glucose;anthropometric indicators;liver and plasma lipidomics; | — |
Countries
China
Contacts
Public ContactHaiqing Guo
Beijing Youan Hospital, Capital Medical University
Outcome results
None listed