intracranial hyperbaric decompression craniotomy
Conditions
Interventions
Control group:convential induction
topical anesthesia:Throat and endotracheal surface anesthesia prior to intubation
Sponsors
Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 16-80 years; 2. Patients with a history of brain trauma and confirmed cerebral herniation by brain CT or MRI; 3. Intracranial hypertension; 4. Patients with a Glasgow coma score of GCS<9; 5. Emergency treatment under general anesthesia, cerebral hematoma removal, decompression craniotomy; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Non-emergency, non-decompression craniotomy patients; 2. Severe liver and kidney insufficiency; 3. Patients with secondary brain surgery; 4. Patients with complex systemic injury; 5. Patients with malignant tumors; 6. Pregnant or lactating women; 7. Patients who are allergic to the drugs in this study; 8. Patients who are participating in other studies at the same time; 9. Psychopaths and those who cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;mortality;morbidity in ICU;Lactate dehydrogenase, creatine kinase, Troponin I;concentration of creatinine, urea, uric acid in serum;ALT, AST, ALP, GGTP;postoperative neurological score; | — |
Countries
China
Contacts
Public ContactWei Gao
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed