Tumors
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients with suspected tumors who cannot be clearly diagnosed as tumors using other imaging methods such as ultrasound, CT, MRI, etc. (2) The patient's general condition is acceptable and can tolerate PET examination. (3) Positive individuals with FAP cyclic peptide PET/CT imaging. (4) After previous treatment, there is no satisfactory alternative treatment plan for refractory or progressive advanced/metastatic solid tumors. (5) Age = 18 years old, life expectancy = 6 months. (6) ECOG PS 0 or 1. (7) Diseases that can be measured according to RECIST. (8) There has been no systemic radioactive therapy in the past.
Exclusion criteria
Exclusion criteria: (1) Clinically significant impairment of bone marrow, liver, and kidney function, such as platelet count<75 × 10^9/L, neutrophil count<1.5 × 10^9, hemoglobin concentration<90 g/L or albumin concentration = 25 g/L, GFR<40 ml/min. (2) Simultaneously using nephrotoxic drugs, there has been radiotherapy for a single evaluable lesion in the past (6 weeks) or uncontrollable complications. (3) Those who have fertility requirements within six months and are unable to withstand radiation risks. (4) Non tumor patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SUVmean;TBR;Sensitivity, specificity, accuracy;Dosimetry; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolic tumor volume; | — |
Countries
China
Contacts
Public ContactWang Xinlu
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed