Epilepsy
Conditions
Interventions
perampanel treatment group:NA
Sponsors
Department of Pediatrics, the First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: ?Clinical symptoms and diagnosis in accordance with the 2017 International League Against Epilepsy (ILAE) diagnostic criteria for focal onset epilepsy;?Age between 4 and 18 years;?Receipt of treatment with Perampanel;?Informed consent from the legal guardians of pediatric patients, who are willing to actively participate in the treatment and undergo a follow-up period of at least six months.
Exclusion criteria
Exclusion criteria: ?Poor adherence to the treatment regimen, including inconsistent medication usage, self-adjustment of medication dosage, self-discontinuation of treatment, refusal to undergo regular check-ups, and non-cooperation with follow-up assessments. ?Participants with a follow-up period of less than six months. ?Involvement in concurrent participation in other clinical trials. ?Participants with inaccurate or unreliable clinical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During treatment visits, Proportion of subjects with =50% reduction in seizure frequency from baseline at different time points; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event incidence rate;Drug retention rate at different time points;During treatment visits, Proportion of subjects with seizure-free at different time points;During treatment visits,cognitive improvement at different time points;During treatment visits,sleep quality at different time points; | — |
Countries
China
Contacts
Public ContactLin Xi
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed