laparoscopic liver resection
Conditions
Interventions
Group A:0.9% Saline and binding cuff without inflation
Group B:Remote ischemic preconditioning+0.9% Saline
Group C:Dexmedetomidine and binding cuff without inflation
Group D:Remote ischemic preconditioning and dexmedetomidine
Sponsors
The First Affiliated Hospital of the Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo laparoscopic Hepatectomy; 2. ASA grading I - III; 3. Child-Pugh score: ChildA level or ChilddB level; 4. Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Age35Kg/m2; 3.Electrocardiogram suggests degree II and above or more than double bundle branch block; 4.Liver trauma patients or liver transplant donors; 5.Peripheral vascular diseases or local limb lesions affecting the implementation of remote ischemic preconditioning; 6.Suffering from mental illness that affects cognitive and judgment skills and compliance; 7.Pregnant and lactating women; 8.History of allergy to any investigational drug; 9. Currently participating in other clinical trial studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT; | — |
Secondary
| Measure | Time frame |
|---|---|
| AST;TBIL;DBILI;IBILI;ALP;GGP;ALB;Lac;IL-6;CRP;BUN;Cr;SOD;QoR-15;complications;hospital stay; | — |
Countries
China
Contacts
Public ContactZhenghua Zhu
The First Affiliated Hospital of the Air Force Military Medical University
Outcome results
None listed