Severe acute pancreatitis
Conditions
Interventions
Epidural anesthesia group (EA):After standard skin disinfection, immediately insert EA and slowly inject 6-15 ml of 0.1% ropivacaine and sufentanil (0.5µg/ml), repeated every 6-8 hours
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? 18-65 years old ? Meets the criteria for severe acute pancreatitis (based on the 2012 Atlanta standard) ? Approved by the hospital ethics committee, get an informed consent form from patients and their families
Exclusion criteria
Exclusion criteria: ? Participated in other clinical trials ? There are contraindications for puncture, such as severe abnormalities in coagulation function, intracranial hypertension, tumor occupancy, difficulty in positioning, etc ? Pregnancy or lactation ? Patients with biliary obstruction or acute gallstone cholangitis, and patients with pancreatic cancer or other system tumors ? Patients who use other drugs that may affect the results of the research experiment during treatment ? Local infection affecting the operator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesic effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factors (WBC, PCR, TNF);Improvement rate of abdominal pressure;RASS ;APACHE?; | — |
Countries
China
Contacts
Public ContactXiaofeng Ou
West China Hospital, Sichuan University
Outcome results
None listed