COPD with hypoxia-pulmonary hypertension
Conditions
Interventions
Experimental group:Maxing Xiongting Mixture and Western medicine treatment
Sponsors
Chongqing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The patients with COPD complicated with pulmonary hypertension are in stable stage, and have no respiratory tract infection and acute attack of chronic obstructive pulmonary disease in the past 4 weeks; (2) It conforms to the syndrome of phlegm and blood stasis; (3) Age = 40 years old and<80 years old, regardless of gender; (4) The dose and type of conventional western medicine treatment drugs are fixed in the past month; (5) Not receiving targeted drug treatment; (6) The patient or family member is willing to sign an informed consent form and participate in the study.
Exclusion criteria
Exclusion criteria: (1) Pulmonary hypertension caused by other chronic lung diseases (interstitial lung disease, pneumoconiosis, sleep apnea, etc.) or other reasons; (2) Pregnant women and lactating women; (3) Those who are allergic to the study drug; (4) It is accompanied by serious heart, liver and kidney system diseases or connective tissue diseases in active stage; (5) Patients with right ventricular outflow tract obstruction; (6) Those who lack informed consent or patients do not cooperate and cooperate; (7) Participate in other clinical researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary artery systolic pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;Cardiac color Doppler echocardiography;6min walk test;Borg Dyspnea Score;WHO functional classification;TCM syndrome score;Quality of life scale;HIF-1a;ET-1;NO;NT-proBNP; | — |
Countries
China
Contacts
Public ContactXing An
Chongqing Traditional Chinese Medicine Hospital
Outcome results
None listed