Effect of intravenous dexamethasone on sleep quality after open gynecological surgery

Effect of intravenous dexamethasone on sleep quality after open gynecological surgery: a randomized, double-blind, placebo-controlled parallel study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076930

Enrollment

Unknown

Registered

2023-10-24

Start date

2023-10-25

Completion date

Unknown

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sleep disturbance

Interventions

treatment group:intravenous dexamethasone 8mg

control group :intravenous saline

Eligibility

Sex/Gender

Female

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 18-70 years old, ASA grade I-III, open gynecological tumor surgery, BMI < 35

Exclusion criteria

Exclusion criteria: 1) No ability to sign informed consent, unable to communicate 2) Long-term use of glucocorticoids 3) Coagulation dysfunction 4) Allergic to ropivacaine 5) Other epidural contraindications 6) Long-term poor sleep and a long history of taking sleeping pills 7) Sleep apnea syndrome has been confirmed

Design outcomes

Primary

Measure	Time frame
Sleep Quality ;	—

Secondary

Measure	Time frame
Depression and Anxiety Scale;pain score;Consumption of opioid analgesics (sufentanil);Blood glucose values;	—

Countries

China

Contacts

Public ContactJun Zhang

Fudan university Shanghai Cancer Center

snapzhang@aliyun.com+86 138 1715 3025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026