Study on the Improvement of Polycystic Ovarian Syndrome patients with overweight / obesity by standardizing medical nutrition management and probiotic treatment

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076921

Enrollment

Unknown

Registered

2023-10-24

Start date

2023-11-01

Completion date

Unknown

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovarian Syndrome

Interventions

A(PCOS):None

B:Standardized nutrition management and placebo

C:Standardized nutrition management and probiotic

D(healthy control):None

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Control group: (1) age:18~40, 18.5=BMI<23.9kg/m^2 (2) No history of gastrointestinal diseases such as diarrhea within 4 weeks, and no anomaly in stool exam. (3) No history of allergic diseases such as asthma and allergic cough. (4) No treatment of probiotic, prebiotic, postbiotic or antibiotic within 2 weeks PCOS group: (1)2003 Rotterdam Standard Diagnosis of PCOS (2)BMI =24 kg/m^2 (3) age:18~40

Exclusion criteria

Exclusion criteria: Control group: (1) Received antibiotic/probiotic/prebiotic/postbiotic treatment within three months PCOS group: (1) Diagnosis of endocrine diseases such as Cushing syndrome and congenital adrenocortical hyperplasia (2) Diagnosis of diseases such as adrenal tumors or ovarian tumors. (3) Diagnosis of Myocardial diseases, Liver diseases or Kidney diseases. (2) Diagnosis of allergic, mental illness or depression (3) Diagnosis of severe hepatic and renal insufficiency, cardiovascular disease or other major organic diseases. (4) Patients who can not strictly implement and record diet and exercise in accordance with the regulations (5) Patients who receive sex hormones or drugs that affect glucose and lipid metabolism (6) Patients who have used antibiotics (7) Patients with probiotic intolerance (8) patients with mental illness / depression.

Design outcomes

Primary

Measure	Time frame
Fasting blood glucose ;Insulin;Total cholesterol;Triglyceride;High-density lipoprotein cholesterol;Low-Density Lipoprotein Cholesterol;body weight;waist;Body fat percentage;Body Mass Index;	—

Secondary

Measure	Time frame
gut microbiota;	—

Countries

China

Contacts

Public ContactWu Xiaona

West China Second University Hospital, Sichuan University

7486350@qq.com+86 28 8857 0611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026