Postoperative delirium
Conditions
Interventions
Lidocaine (Group L):From the beginning of anesthesia induction to the end of surgery, the experimental group was infused with lidocaine (initial dose: 1.0 mg/kg, i.v., maintenance dose: 1.0 mg/kg.h, i
Control group:Infusion of equal amount of physiological saline
Sponsors
Nanchong Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists physical status I-III patients aged 65 years or older and under 85 years, with body mass index of 18-28kg/m², scheduled for elective hip replacement surgery, and informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: The score of higher education was less than 24 points, secondary education was less than 23 points, primary education was less than 20 points, and illiteration was less than 18 points in mini-mental state examination (MMSE). Body weight 100 kg; Symptomatic cardiovascular and cerebrovascular diseases (such as refractory heart failure, stroke, etc.); Severe liver, kidney and other important organ dysfunction; Patients who are allergic to lidocaine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Types of postoperative delirium;Severity of postoperative delirium;Opioid consumption;The duration of operation;Intraoperative blood loss;Fluid infusion volume;Intraoperative urine volume;Anesthesia emergence time;Extubation time of tracheal tube;Length of stay in postanesthesia care unit;Postoperative pain;Time to ambulation;Length of hospital stay;Hypotension;Hypertension;Bradycardia;Tachycardia;Nausea and vomiting;Local anesthetic poisoning;Satisfaction;Hospitalization expenses; | — |
Countries
The People's Republic of China
Contacts
Public ContactYi Tang
Nanchong Central Hospital
Outcome results
None listed