Hiccup
Conditions
Interventions
Group A:Remazolam 5mg at a rate of 15S and propofol 1.0 mg/kg
Group B:Remazolam 5mg at a rate of 30S and propofol 1.0 mg/kg
Group C:Remazolam 5mg at a rate of 45S and propofol 1.0 mg/kg
Group D:Remazolam 5mg at a rate of 60S and propofol 1.0 mg/kg
Group E:Group E was only induced by 2.0 mg/kg propofol without remazolam intervention
Sponsors
The Second Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)Age 20-65 years old; (2) Gender is not limited; (3)American Society of Anesthesiologists (ASA) Level I to II; (4) The body mass index (BMI) is 18.0-24.0 kg/m2.
Exclusion criteria
Exclusion criteria: (1) Patients with difficult airway (neck mobility limited, Mallampati grades 3-4, nappe-chin distance <6cm), basal SpO2<90%, or sleep apnea syndrome; (2) long-term use of sedative hypnotic patients; (3) Patients with contraindications of benzodiazepines, opioids and propofol; (4) Changes in endoscopy caused by gastrointestinal bleeding, gastrointestinal perforation, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hiccup; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset of anesthesia;Endoscopic operation time; | — |
Countries
China
Contacts
Public ContactHaitao Yang
The Second Affiliated Hospital of Dalian Medical University
Outcome results
None listed