postinduction hypotension
Conditions
Interventions
Group E:Group E was anesthetised with etomidate 0.3mg/kg, fentanyl 2-4ug/kg, rocuronium 0.6mg/kg
Group R:Group R was anesthetized with remazolam 0.3mg/kg, fentanyl 2-4ug/kg, rocuronium 0.6mg/kg
Group C:Group C was anesthetized with cypofol 0.4mg/kg, fentanyl 2-4ug/kg, rocuronium 0.6mg/kg
Sponsors
Dalian Municipal Central Hospital of Dalian University of Technology
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Elderly (age > 65 years old); 2.ASA Level I-III; 3. Patients undergoing elective general anesthesia; 4. Patients who signed informed consent and subject statement.
Exclusion criteria
Exclusion criteria: 1. Severe cardiovascular system diseases; 2. Severe respiratory disease; 3. History of long-term use of psychotropic drugs and cognitive dysfunction; 4. Abnormal kidney function; 5. Liver disease; 6. History of seizures; 7. Adrenal cortical insufficiency or taking steroid drugs; 8. Allergic or contraindicated to the investigational drug and its components; 9. Participated in other clinical trials as a subject within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-induction hypotension;MAP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of vasopressors;injection pain;myoclonus;SBP;DBP; | — |
Countries
China
Contacts
Public ContactCongjie Bi
Dalian Municipal Central Hospital of Dalian University of Technology
Outcome results
None listed