Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Meet the diagnostic criteria of KOA; ? Age 40-80 years, disease duration = 6 months; ?Visual Analogue Scale (VAS) =3 for most of the time in the past 1 month; ?Signed informed consent.
Exclusion criteria
Exclusion criteria: ? All subjects who have had gastrointestinal diseases, taken antibiotics or agents capable of affecting intestinal flora, such as probiotics and prebiotics, in the 8 weeks prior to sampling; ? Other diseases that produce joint symptoms, such as metabolic bone disease, acute trauma; ? Gouty arthritis, rheumatoid arthritis and other non-degenerative arthritis and joint deformities; ?Pregnancy, mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale;Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| joint space;osteophyte; | — |
Countries
CHINA
Contacts
College of Traditional Chinese Medicine, Chongqing Medical University