Endoscopic retrograde cholangiopancreatography(ERCP)
Conditions
Interventions
Group A:Propofol 1 mg/kg+ afentanil 10 ug/kg was induced, 4 mg·kg-1·h-1 and afentanil 0.25-1 ug·kg-1·min-1 were maintained
Group B:Ciprofol 0.3 mg/kg+ afentanil 10 ug/kg was induced, 1 mg·kg-1·h-1 and afentanil 0.25-1 ug·kg-1·min-1 were maintained
Group C:Ciprofol 0.2 mg/kg+ afentanil 10 ug/kg was induced, 1 mg·kg-1·h-1 and afentanil 0.25-1 ug·kg-1·min-1 were maintained
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.The patient's mental state is good and communication is barrier-free. 2.Obtaining informed consent. 3.Over 65 years of age . 4.No history of allergy to related narcotic drugs. 5.ASA grade ?-?.
Exclusion criteria
Exclusion criteria: 1.Based on clinical judgment and known difficult tracheal intubation is considered a "difficult airway" and/or difficult intubation. 2.serious cardiopulmonary impairment or any other indication that surgery must be performed under general anesthesia with endotracheal intubation. 3.Patients judged to be at serious risk of pulmonary inhalation. Possible risk factors for aspiration include: increased stomach contents; Delayed gastric emptying; No fasting (solid food <6 hours, clear liquid <2 hours); Increased risk of reflux: uncontrolled or symptomatic gastroesophageal reflux, esophageal stenosis, and achalasia. 4.Criteria for emergency surgery and any other general anaesthesia requiring endotracheal intubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset of anesthesia;Operation time;Recovery time;Exit time;Ciprofol , propofol and opioid use;The adverse reactions that occurred during the operation; | — |
Countries
China
Contacts
Public ContactHaiyu Xie
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed