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Corneal characteristics and heritability of parents of keratoconus patients

Corneal characteristics and heritability of parents of keratoconus patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076886
Enrollment
Unknown
Registered
2023-10-23
Start date
2023-10-30
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratoconus di

Interventions

parents of keratoconus group:NA

Sponsors

Qingdao Eye Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 66 Years

Inclusion criteria

Inclusion criteria: 1. Patients in the keratoconus group had a history of myopic astigmatism according to Rabinowitz[24] diagnostic criteria; Corrected vision 47D. The diopter difference between 3mm below corneal center and 3mm above corneal center is >3D; The diopter difference of the anterior central corneal surface of both eyes was >1D. 2. Parents of keratoconus patients 3. The parents, gender and age of the refractive surgery patient were matched with the parents of the keratoconus patient

Exclusion criteria

Exclusion criteria: 1. Eye or systemic diseases, eye trauma, transplantation or other comprehensive diseases affecting eye health; 2. Have a history of allergies; 3. Stop wearing soft contact lenses for more than 2 weeks and hard contact lenses for more than 4 weeks 4. Poor medical obedience, can not cooperate with the examination

Design outcomes

Primary

MeasureTime frame
Corneal epithelial thickness;Itrace examine;axial length;maximal keratometry;Final D;thinnest point pachymetry;keratometry in the flat/steep meridian ;anterior surfaces elevation of the cornea;CBI;TBI;ssi;SPA-1;central corneal thickness;Ambrósio relational thickness horizontal ;integrated radius;Deformation amplitude ratio max 2 mm ;posterior surfaces elevation of the cornea;

Secondary

MeasureTime frame
Computer refraction;

Countries

China

Contacts

Public ContactDu Xianli

Qingdao Eye Hospital of Shandong First Medical University

lilibestever@126.com+86 151 9255 2255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026