Acute ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Clinical signs and symptoms meet acute ischemic stroke; 2)diagnosed as acute ischemic stroke confirmed by CT/MRI; 3)Written informed consent obtained from patients or their legal representatives.
Exclusion criteria
Exclusion criteria: 1) intracranial hemorrhage confirmed by head CT or MRI; 2) systolic blood pressure > 220mmHg or diastolic blood pressure > 130mmHg and could not be controlled with antihypertensive drugs; 3) a history of bleeding (gastrointestinal or urinary tract bleeding) or major surgery in a past month; 4) expected inability to complete follow-up; 5) Patients who were deemed by the investigators to be unfit for study participation were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of 90-day modified RANKIN scale (mRS) score 0-1 (%);mortality at 90 days;Incidence of symptomatic intracranial hemorrhage within 48 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Shift in the distribution of mRS scores at 90 days;Proportion of patients with functional independence (mRS score 0 to 2) at 90 days; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Chongqing Medical University