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A prospective, multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke

A prospective, multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076878
Enrollment
Unknown
Registered
2023-10-23
Start date
2023-10-30
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Intravenous thrombolysis treatment group:NA
conventional western medicine treatment group:NA

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1)Clinical signs and symptoms meet acute ischemic stroke; 2)diagnosed as acute ischemic stroke confirmed by CT/MRI; 3)Written informed consent obtained from patients or their legal representatives.

Exclusion criteria

Exclusion criteria: 1) intracranial hemorrhage confirmed by head CT or MRI; 2) systolic blood pressure > 220mmHg or diastolic blood pressure > 130mmHg and could not be controlled with antihypertensive drugs; 3) a history of bleeding (gastrointestinal or urinary tract bleeding) or major surgery in a past month; 4) expected inability to complete follow-up; 5) Patients who were deemed by the investigators to be unfit for study participation were excluded.

Design outcomes

Primary

MeasureTime frame
The rate of 90-day modified RANKIN scale (mRS) score 0-1 (%);mortality at 90 days;Incidence of symptomatic intracranial hemorrhage within 48 hours;

Secondary

MeasureTime frame
Shift in the distribution of mRS scores at 90 days;Proportion of patients with functional independence (mRS score 0 to 2) at 90 days;

Countries

China

Contacts

Public ContactYangmei Chen

The Second Affiliated Hospital of Chongqing Medical University

chenym1997@sina.com+86 136 0834 8562

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026