Anal fistula
Conditions
Interventions
Experimental group:Modified External Sphincter-preserving Surgery
Control group:Ligation of Intersphincteric Fistula Tract
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years old; 2. High trans-sphincter anal fistula (the track involved >1/3 of the external sphincter), confirmed by contrast enhanced MRI of anus; 3. Patients and their families understand and are willing to participate in the study, sign informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with inflammatory bowel disease, such as Crohn's disease, ulcerative colitis, etc; 2. Previous history of malignant colorectal tumors within 5 years; 3. Patients with severe impairment of liver function, kidney function and cardiopulmonary function, coagulation dysfunction, or other underlying diseases that might not tolerate surgery; 4. History of serious mental illness 5. Pregnant or lactating women 6. Patients with history of diabetes, tuberculosis and other diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Initial healing rate within 6 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal incontinence score 1 year after surgery;Postoperative quality-of-life score;Postoperative wound healing time;Postoperative complication rate;Overall healing rate within 6 months after surgery; | — |
Countries
China
Contacts
Public ContactLiu Zhimin
The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed