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Hydromorphone patient-controlled analgesia versus conventional analgesia for perioperative analgesia in thermal ablation: a prospective, multicenter, randomized controlled clinical study

Hydromorphone patient-controlled analgesia versus conventional analgesia for perioperative analgesia in thermal ablation: a prospective, multicenter, randomized controlled clinical study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076865
Enrollment
Unknown
Registered
2023-10-23
Start date
2024-01-15
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thermal ablation for perioperative analgesia

Interventions

Group H:Hydromorphone PCA
Group M:Morphine, non-PCA

Sponsors

Medical Ethics Committee, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate and sign the informed consent form in person; 2. Patients undergoing elective tumor thermal ablation; 3. Eastern Cooperative Oncology Group (ECOG) performance status =2;

Exclusion criteria

Exclusion criteria: 1. History of severe cardio-cerebrovascular and respiratory diseases; 2. Patients with allergy to test drugs or contrast agents; 3. Patients with opioid addiction; 4. Patients with cognitive impairment; 5. Have participated in other clinical investigators within the previous 30 days.

Design outcomes

Primary

MeasureTime frame
The highest intraoperative pain score;

Secondary

MeasureTime frame
NRS scores were obtained at each time point;Satisfaction evaluation of analgesic effect;Daily opioid equivalent dose;Number of rescue medications;Length of postoperative hospital stay;Duration of SURGERY;QOR-40;

Countries

China

Contacts

Public ContactChuansheng Zheng

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

hqzcsxh@sina.com+86 133 2970 2158

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026