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Study pre-IVF incubation on oocyte quality, fertilization, early embryonic development and pregnancy outcomes

Study pre-IVF incubation on oocyte quality, fertilization, early embryonic development and pregnancy outcomes

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076852
Enrollment
Unknown
Registered
2023-10-22
Start date
2023-11-01
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Treatment group:short time in vitro maturation
Control group:None

Sponsors

Reproductive Medicine Center of the Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1.Female, 20 years old = Age = 30 years old; 2. Confirmed as tubal infertility, with an AMH value of = 2; 3. On the second day of menstruation, vaginal ultrasound showed more than 10 antral follicles in both ovaries; 4. Not using ovarian stimulation to promote ovulation within 3 months before entering the experiment; 5. Subjects who sign informed consent forms.

Exclusion criteria

Exclusion criteria: 1. Previous history of ovarian surgery, ovarian cysts, and acute pelvic inflammation; 2, the man needs a second generation of insemination; 3. Previous stage III or IV endometriosis, adenomyosis, uterine fibroids, endometrial polyps, abnormal uterine morphology, and scarred uterus; 4. Hydrosalpinx and serious pelvic adhesion in the past; 5, both husband and wife have cardiovascular, liver, kidney and hematopoietic system, thyroid disease and other serious primary diseases and mental patients; 6. Known history of alcohol addiction or drug abuse; 7. Patients identified by medical history, physical examination, clinical laboratory examination, etc., as having other medical conditions that increase the risk of using the experimental culture solution or that may confuse the analysis and/or interpretation of the study results; 8. Other circumstances that the researcher considers inappropriate to participate in this experiment; 9. Patients who participated in other clinical studies 3 months before the trial.ts

Design outcomes

Primary

MeasureTime frame
Blastocyst formation rate;

Secondary

MeasureTime frame
Ovum maturation rate;Normal fertilization rate;Good embryo rate;Blood beta-HCG positive rate;implantation rate;clinical pregnancy rate;

Countries

China

Contacts

Public ContactRicheng Chian

Reproductive Medicine Center of the Shanghai Tenth People's Hospital

rchian@126.com+86 189 1768 7092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026