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Clinical effect of dexamethasone on febrile symptoms after endovascular aortic aneurysm repair

Effect of prophylactic administration of dexamethasone before anesthesia on postoperative fever in patients undergoing endovascular repair of aortic aneurysm

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076826
Enrollment
Unknown
Registered
2023-10-20
Start date
2023-10-23
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic aneurysm

Interventions

Dexamethasone group:No
Control group:No

Sponsors

Anesthesiology of Shanxi Bethune Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ? According to the history, clinical manifestations and imaging examination, the diagnosis was confirmed as abdominal aortic aneurysm; ? Patients who have recovered after endovascular repair of aortic aneurysm; ? Age: 18-65 years old; ? The American Society of Anesthesiologists (ASA) classification of anesthesia is grade I to IV.

Exclusion criteria

Exclusion criteria: (1) Preoperative white blood cells greater than 10×10^9/L; (2) Acute aortic dissection or aortic aneurysm rupture; (3) Positive blood culture; (4) Confirmation of urinary system or incision infection; (5) aortitis, or autoimmune or connective tissue disease; (6) Malignant tumors; (7) Diseases of the blood system or pre-operative wasting coagulation disease; (8) Renal insufficiency dialysis; (9) Implant history; (10) Use of anti-inflammatory, immunosuppressive or chemotherapeutic drugs in the past 3 months; (11) Aortic trauma or surgery within the past 1 month; (12) EVAR intervenes again; (13) From EVAR to open surgery; (14) To determine the cause of death, due to acute intraoperative massive bleeding; (15) Serious lack of clinical data; (16) Patients with dexamethasone allergy, hyperglycemia and related dexamethasone contraindications.

Design outcomes

Primary

MeasureTime frame
Body temperature;

Secondary

MeasureTime frame
Duration of fever;Fever frequency;White blood cell count;Platelet count;High-sensitivity C-reactive protein;Interleukin 6;

Countries

China

Contacts

Public ContactQiPeng Xie

Anesthesiology of Shanxi Bethune Hospital

yuengqingyan@163.com+86 138 3468 6541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026