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The mechanism of Shenfu injection in the treatment of sepsis based on intestinal microbiota metamogenics

The mechanism of Shenfu injection in the treatment of sepsis based on intestinal microbiota metamogenics

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076817
Enrollment
Unknown
Registered
2023-10-19
Start date
2023-10-20
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Conventional treatment group:Performing routine treatment
Shenfu Injection Treatment group:On the basis of routine treatment, administer Shenfu Injection for treatment

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were as follows: (1) met the clinical diagnostic criteria in accordance with recommendations from the Third International Consensus Definitions for Septic Shock (Singer et al., 2016); (2) age of 18 to 79 years; (3) persisting hypotension requiring vasopressors to maintain a mean arterial pressure of 65 mm Hg or higher despite adequate volume resuscitation.

Exclusion criteria

Exclusion criteria: The exclusion criteria were as follows: (1) hypersensitivity to SFI; (2) confirmed pregnancy; (3) with terminal illnesses; and (4) unable to understand the study protocol or unwilling to participate in the study after explanation.

Design outcomes

Primary

MeasureTime frame
Fecal DNA;

Secondary

MeasureTime frame
WBC;CRP;PCT;IL-6;APACHE II;SOFA;age;gender;heart rate;

Countries

China

Contacts

Public ContactZhang Suming

The Affiliated Hospital of Xuzhou Medical University

samuel3766@126.com+86 189 1347 9909

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026