Lack of teeth
Conditions
Interventions
tooth loss group:None
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The subjects are 18 years old and above, and 80 years old and below; (2) Implant surgery is required (3) the subject signs written informed consent; (4) Overall good health condition and adherence to good oral hygiene conditions; (5) There is no infection or tooth extraction residue at the implant site;
Exclusion criteria
Exclusion criteria: 1) Contraindications for general implant surgery; (2) Uncontrolled diabetes; (3) Any signs of immunosuppression; (4) Has received radiation therapy for the head and neck; (5) Previous or current treatment with bisphosphonates; (6) Drug abuse; (7) Progressive periodontitis; (8) Smoking more than 20 cigarettes per day; (9) Poor oral hygiene; (10) Mental disorders; (11) Unable to complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gene expression level;Peri-implant bone resorption; | — |
Secondary
| Measure | Time frame |
|---|---|
| protein expression level;Soft tissue changes around the implant; | — |
Countries
China
Contacts
Public ContactFan Yang
Zhejiang Provincial People’s Hospital
Outcome results
None listed