Scoliosis
Conditions
Interventions
Remimazolam group (group R):The selection of sedative drugs is: Remimazolam+Propofol
Dexmedetomidine group (Group D) :The selection of sedative drugs is: Dexmedetomidine+Propofol
Propofol group (group P):The selection of sedative drugs is: Propofol
Sponsors
The First People's Hospital of Yunnan Province (The Affiliated Hospital of Kunming University of Science and Technology)
Eligibility
Sex/Gender
All
Age
10 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Participants scheduled for elective SOSCS; 2. American Society of Anesthesiologists (ASA) physical status I–III; 3. Age 10–50 years; 4. Ability and willingness to provide informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of organic central nervous system disorders or impaired consciousness; 2. Severe coagulopathy; 3. Severe comorbidities, such as severe pulmonary hypertension, hepatic encephalopathy, acute myocardial infarction, acute heart failure, or hepatorenal failure; 4. Psychiatric disorders or communication barriers precluding cooperation during wake-up testing; 5. Participnats on concomitant medications with known interaction potential that may increase adverse reactions; known allergy to any study medication; 6. History of substance abuse or opioid tolerance; 7. Conditions including epilepsy, cortical lesions, cranial defects, intracranial hypertension, or presence of intracranial hardware; 9. Any condition deemed unsuitable for study participation by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The wake-up time;The wake-up quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuroelectrophysiological monitoring indicators;Cerebral State Index;Hemodynamic monitoring (HR+MAP);Satisfaction; | — |
Countries
China
Contacts
Public ContactJin Hua
The First People's Hospital of Yunnan Province (The Affiliated Hospital of Kunming University of Science and Technology)
Outcome results
None listed