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Exploring the Mechanism of Resistance to Radiochemotherapy in Colorectal Mucous Adenocarcinoma by Combination of ATAC seq and RNA seq

Exploring the Mechanism of Resistance to Radiochemotherapy in Colorectal Mucous Adenocarcinoma by Combination of ATAC seq and RNA seq

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076785
Enrollment
Unknown
Registered
2023-10-18
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Mucinous adenocarcinoma:None
Adenocarcinoma with mucinous component:None
Non-mucinous adenocarcinoma:None

Sponsors

Peking University Shougang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 93 Years

Inclusion criteria

Inclusion criteria: 1) Colorectal adenocarcinoma or mucinous adenocarcinoma with definite pathological diagnosis; 2) Underwent radical surgical resection (R0 resection);

Exclusion criteria

Exclusion criteria: Other pathological types of coloractal cancer other than non-mucinous adenocarcinoma (extracellular mucus accounting for less than 5% of the tumor volume), adenocarcinoma with mucinous component (extracellular mucus accounting for more than 5% and less than 50% of the tumor volume), and mucinous adenocarcinoma (extracellular mucus accounting for 50% and more of the tumor volume); multiple primary cancers; history of malignancy; Hereditary colorectal cancer.

Design outcomes

Primary

MeasureTime frame
Overall survival;Cancer-specific survival;

Secondary

MeasureTime frame
Recurrence-free survival;

Countries

China

Contacts

Public ContactJin Gu

Peking University Shougang Hospital;Peking University Cancer Hospital

zlguj@bjmu.edu.cn+86 88196086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026