Skip to content

Effect and mechanism of Chai-gui decoction on liver stagnation and blood deficiency hypertension

Effect and mechanism of Chai-gui decoction on liver stagnation and blood deficiency hypertension

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076783
Enrollment
Unknown
Registered
2023-10-18
Start date
2022-04-22
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Combination treatment group:Chai-gui decoction (Chinese medicine) and antihypertensive drugs
Standard tratment group:Standard treatment with antihypertensive drugs

Sponsors

Wuxi Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 95 Years

Inclusion criteria

Inclusion criteria: ? Meet the above criteria of western medicine diagnosis and TCM syndrome differentiation for hypertension; ?Measure blood pressure below 220/130 mmHg; ?The age ranged from 18 to 95 years (including boundary values); ? Subjects gave informed consent and signed informed consent voluntarily.

Exclusion criteria

Exclusion criteria: ? Patients with secondary hypertension; ? Allergic constitution and allergic to the drug; ? Patients diagnosed with severe arrhythmia, cardiac structural disease and other acute cardiac diseases or complicated with cerebral infarction (acute phase), severe pulmonary insufficiency and other acute diseases; ? Renal dysfunction, male serum creatinine > 2.5 mg/dl (> 220 umol/L), female serum creatinine > 2.0 mg/dl (> 175 umol/L); Patients with obvious liver disease or liver function test values higher than 2 times the upper limit of normal; ?Pregnant or preparing to be pregnant women; Lactating women are allergic to known components of the study drug; ? Patients with malignant tumors or who were deemed inappropriate by the investigator to participate in the trial; ? patients with serious hematopoietic diseases; ? Severe mental patients; ? Those who have participated in or are currently participating in other clinical trials within the past three months; ? Patients who refuse to submit to an investigation.

Design outcomes

Primary

MeasureTime frame
Blood pressure;Scores for TCM syndromes;

Secondary

MeasureTime frame
Compliance rate of enhanced BP reduction;

Countries

China

Contacts

Public ContactHu Xiaohai

Wuxi Hospital of Traditional Chinese Medicine

13937673321@qq.com+86 139 3767 3321

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026