nasopharyngeal carcinoma
Conditions
Interventions
Gold Standard:The biopsy pathology of the lesion or clinical outcomes obtained from follow-up.
The diagnosis of CEUS with Sonazoid for the lesion
MRI diagnosis
18F-FDG PET/CT diagnosis.
Sponsors
Sun Yat-Sen University Cancer Center IRB
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Nasopharyngeal carcinoma was diagnosed histologically. (2) The tumor stage was T1-T4, N0-N3, M0-M1 (AJCC 8th). (3) All patients underwent bilateral parotid conventional ultrasound, contrast-enhanced ultrasound (sonazoid), and head and neck MRI before treatment. (4) Patients who have complete clinical and pathological data.
Exclusion criteria
Exclusion criteria: (1) Patients with other malignant tumors. (2) Patients with cardiovascular and cerebrovascular diseases (such as hypertension, coronary heart disease) or allergy to protein are not suitable for CEUS (sonazoid). (3) Patients who were unable to undergo MRI due to claustrophobia, metal implants, allergy to contrast media and other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic features of conventional ultrasound and contrast-enhanced ultrasound;Accuracy of conventional ultrasound combined with contrast-enhanced ultrasound;Sensitivity of conventional ultrasound combined with contrast-enhanced ultrasound ;Specificity of conventional ultrasound combined with contrast-enhanced ultrasound ;The positive predictive value of conventional ultrasound combined with contrast-enhanced ultrasound ;The negative predictive value of conventional ultrasound combined with contrast-enhanced ultrasound ;Kappa value of conventional ultrasound combined with contrast-enhanced ultrasound ;AUC values of conventional ultrasound combined with contrast-enhanced ultrasound ; | — |
Countries
China
Contacts
Public ContactLiu Longzhong
Sun Yat-Sen University Cancer Center
Outcome results
None listed