Mechanical ventilation patients
Conditions
Interventions
Test group:First, collect respiratory mechanics indicators with pressure support ventilation for 30 minutes, and then use adaptive command ventilation for 30 minutes to collect respiratory mechanics i
control group:The indexes of respiratory mechanics were collected by adaptive command ventilation for 30 minutes, and then by pressure support ventilation for 30 minutes.
Sponsors
Yijishan Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Improvement or removal of the cause of mechanical ventilation; (2) Oxygenation index>200 mm Hg; Positive end expiratory pressure (PEEP) = 5-8 cm H2O; Inhalated oxygen concentration = 0.4; Arterial blood pH>7.30, arterial oxygen partial pressure>50 mm Hg; (3) Hemodynamics are stable and do not require treatment with vasoactive drugs or small doses of vasoactive drugs (such as dopamine<5-10 µ G · kg-1 · min-1); (4) Having the ability to breathe autonomously and effectively cough; (5) No blood sugar and electrolyte metabolism disorders; (6) No fever.
Exclusion criteria
Exclusion criteria: (1) Uncontrolled systemic infection; (2) Hemodynamic instability; (3) Previous or ongoing neuromuscular diseases such as myasthenia gravis and Guillain Jilin ballet syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| driving pressure;Work of Breathing;Peak pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| compliance;pplat;PEEPi;Oral closing pressure;The ratio of tidal volume to ideal body weight;PIP;Inspiratory peak flow rate;Inspiratory image resistance;Expiratory resistance; | — |
Countries
China
Contacts
Public ContactYingying Wang
Yijishan Hospital of Wannan Meical Colleged
Outcome results
None listed